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Analysts' Checklist for Undertaking a Systematic Review

This checklist should only be used in conjunction with the Guidance Notes on Systematic Review.

Analysts proposing to undertake a systematic review for the first time are also advised to take a structured course on the topic, such as the Government Social Research Unit course on ‘Methods for Synthesis’. For more information on GSR courses see the GSR website.

Formulating an Answerable Question

Does the central question of the review clearly address the following points?
The policy intervention for which evidence is sought
The population or sub-groups that the policy is expected to effect
The outcomes that the policy intervention is expected to achieve
The context in which the policy will operate

Searching for Relevant Studies

Have the following steps of a search strategy been planned?:
The searching of appropriate electronic/internet sources
The searching of appropriate print sources (e.g. journals, textbooks, research reports)
The hand searching of appropriate print sources
The searching of 'grey' (i.e. unpublished) literature

Critically Appraising Studies Found

Has the existing literature been sifted for quality and validity using the criteria below?
The appropriateness of the questions, populations and outcomes addressed
Evidence of selection bias in the primary studies
Evidence of performance bias in the primary studies
Evidence of attrition bias in the primary studies
Evidence of detection bias in the primary studies
What criteria will be used for including and excluding primary studies

Extracting Data from Included Studies

Has a strategy been planned for extracting data from the included studies that considers the issues below?
A data collection form recording how, and why, data were extracted from included studies
Information about the characteristics of included studies
Verification of study eligibility for the review
Details of study characteristics
Details of study methods
Details of study participants (i.e populations and sub-groups)
Details of study interventions
Details of study outcomes and findings
Reliability check for data collection/extraction

Analysing and Presenting the Findings

The analysis and presentation of the findings of the included studies should address the questions below
What comparisons should be made (e.g. by interventions studied, participants included, outcomes measured)?
What study results are needed for each comparison?
What assessments of validity are to be used in the analysis?
Is any other/additional data or information needed from authors of studies included in the review?
Do the data from different studies need to be transformed for the review's analysis?
How is the heterogeneity/homogeneity of studies to be determined?
Is a meta-analysis of findings possible?
What are the main findings of the review?
What are the likely effect sizes of the proposed policy intervention, net of the counterfactual?
What are the main caveats and/or qualifications of the findings of this review?

Interpreting the Findings

The interpretation of the findings of the review must address the following questions
What is the strength of the evidence from the review?
How applicable are the results of the review to 'real life' policy and practice?
What does the review say about the costs and benefits of the proposed intervention?
What trade-offs are suggested by the review between expected benefits, harm and costs (including opportunity costs)?

What mediating factors emerge from the review that might affect the implications for policy and practice in different contexts?

Summarising the Implications for Policy and Practice

What are the 'take home' messages for policy making and/or practice?
What are the 'take home' messages for future research in this area?